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The five formulas made contain avicel PH 102 and amprotab as binders and crushers and the expected results such as shape and durability as desired. Results: The results of phytochemical screening of simplicia and viscous plant extract showed the presence of alkaloids, polyphenols, tannins, and flavonoids as secondary metabolites. niruri extract as the active substance or not. Also, check whether the resulting tablets still contain P. Tablet print mass and quality of the resulting tablets were then evaluated.
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niruri extract as the active ingredient, avicel PH 102 and amprotab with varying concentrations as filler, talcum, and magnesium stearate as a lubricant and Aerosil®200 vv as an adsorbent. Each formula contains a similar concentration of P.
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niruri extract using a direct compressed method with a variation of concentration of filler. Then designed five kinds of tablet formulas of P. First performed phytochemical screening to determine the content of secondary metabolites. niruri plant was collected and determined at the Laboratory of Plant Taxonomy, Universitas Padjadjaran. Objective: The aim of the present study was to obtain an optimized formula of meniran ( Phyllanthus niruri L.) extract tablets that fulfilled the requirements as a good pharmaceutical preparation based on Indonesian Pharmacopoeia IV and USP XVII. Meniran, Phyllanthus niruri, Directly compressed tablet, Formulation, Avicel PH102 Abstract Faculty of Pharmacy, Universitas Padjadjaran,ĢDepartment of Pharmaceutics (Apothecary Programme), Faculty of Pharmacy, Universitas Padjadjaran, Indonesia 45363